BIOASSAY OF INSULIN BIOASSAY OF D-TUBOCURARINE MERITS OF BIOASSAY DEMERITS OF BIOASSAY REFRENCES. is being done through. Bioassay, official method, adrenaline, digitalis, d-tubocurarine, heparin, insulin, oxytocin, gonadotropin, chorionic gonadotropin, urokinase, streptokinase. Second 4 x 4 latin square bioassay was performed using a series: with a The presence of d-tubocurarine was demonstrated in the Peruvian.

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The total amount of test sample required to produce the endpoint is compared with the total amount of the d-tubocurafine sample required to produce similar endpoint. It is a perfect in vitro model.

Plays an important role in breathing It helps to keep internal organ intact. First group will receive standard sample and the second group will receive the sample under test. Upload from Desktop Single File Upload.

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Screening Methods In Pharmacology. Those rabbits which received the standard sample on the first day will be given test sample on the second day of expt.


Rectus abdominis muscle is a paired muscle running vertically on each side of the anterior wall. Automatically changes to Flash or non-Flash embed.

PHARMACOLOGY: Bioassay of D-Tubocurarine

Newer Post Older Post Home. Receptors present in Rectus muscle. They mainly respond to the acetyicholine released from motor neuron terminal. Head drop after injection. Bioassay of D-Tubocurarine 1.

D-tuobcurarine percentage reduction at each dose levels is calculated and log dose response curve of the standard drug is plotted. Rabbits recover immediately from the effect of curarization. Minimum 8 rabbits are used. Each rabbit is placed in a holder with its head protruding outside.


A linear response will be obtained. Numerous small segmental contribution coming from lower inter costal arteries. Pharm 1 st semester Phamacology Under the Guidance of Mr.


Two similar contractions with the same concentration of acetylcholine are obtained. Bioassay of D- Tubocurarine. In order to view it, please contact the author of the presentation. Functions It is an important postural muscle. The responses are recorded using isotonic frontal writing lever with 1 G.


WordPress Embed Customize Embed. Go to Application Have a question? Have a nice day. Location of Rectus muscle. Acetylcholine contraction is recorded on slow moving drum for 90 sec. Injection should be given at a rate of 0. Blood Supply It has several sources for arterial blood supply. Receptors The rectus abdominis muscle of frog mainly rich of Nicotinic receptor.

Location The rectus abdominis is a long flat muscle, which extends along the whole length of the front of the abdomen. Presentation Description No description available. The muscle is stabilized for min. College bioassau Pharmacy, Ahmedabad.

D-tubocurarjne Das Choudhury M. Infusion is continued till the rabbit will not be in a position to hold its head erect or there will be no response by focussing light on the eyes and the neck gets elongated and toneless. Share to Twitter Share to Facebook. Conclusion Rectus abdominis muscle of frog has various importance in pharmacology.